#Replication

DNA polymerase synthesize, repair, and replicate DNA by adding complementary nucleotides to a growing strand in the 5’ ➡️ 3’direction. They ensure high-fidelity genome duplication and repair, utilizing template-directed, precise base pairing during cell division. #dna #dnapolymerase #celldivision #dnareplication #replication

word on my nucleotides source fun biology "During elongation, an enzyme called DNA polymerase adds DNA nucleotides to the 3' end of the template. Because DNA polymerase can only add new nucleotides at the end of a backbone, a primer sequence, which provides this starting point, is added with complementary RNA nucleotides. This primer is removed later, and the nucleotides are replaced with DNA nucleotides. One strand, which is complementary to the parental DNA strand, is synthesized continuously toward the replication fork so the polymerase can add nucleotides in this direction. This continuously synthesized strand is known as the leading strand. Because DNA polymerase can only synthesize DNA in a 5' to 3' direction, the other new strand is put together in short pieces called Okazaki fragments. The Okazaki fragments each require a primer made of RNA to start the synthesis. The strand with the Okazaki fragments is known as the lagging strand. As synthesis proceeds, an enzyme removes the RNA primer, which is then replaced with DNA nucleotides, and the gaps between fragments are sealed by an enzyme called DNA ligase." #biology #dna #genetics #premed #biochem #dnapolymerase #replication

DNA replication is the process by which a cell makes an exact copy of its DNA before cell division. • Occurs in the nucleus (in eukaryotic cells) • Happens during the S phase of the cell cycle • It is semi-conservative (each new DNA has one old strand + one new strand) Main steps: 1️⃣ Unwinding – DNA helicase opens the double helix 2️⃣ Base pairing – Free nucleotides pair with exposed bases 3️⃣ Elongation – DNA polymerase builds the new strand (5′ → 3′) 4️⃣ Joining – DNA ligase joins Okazaki fragments Important enzymes: 🧪 Helicase 🧪 DNA polymerase 🧪 Primase 🧪 Ligase Result: Two identical DNA molecules ✨ #معلومات_طبية #هل_تعلم #صحة#تحليلات #مختبرات #medical #lab #cbc #stool #parasitology #microbiology #labtips #Biology #DNA #Replication #MedicalContent 🧠🧬 Follow for more information.

DNA Replication overview. @microbiologynotes #replication #dnafamily #biochemistrynotes #microbe

Bacteria vs Bacteriophage 👹😈 #reel #bacteria #bacteriophage #science #biology #destroy #earth #insects #attachment #injection #dna #replication #transcription #lysis #release #fy #facts #viralreels

To seperate DNA strands is function of helicase enzyme😂 #dna #replication #biology #instagram #trending #balakrishna #funny #reels

🧬 PART 4 | The unseen universe unfolding inside you every second. The machinery of life is more stunningly complex than any sci-fi film. This extraordinary animation, spanning over a decade of scientific visualization, shows the beautiful, non-stop process of DNA replication and repair. Every second, countless molecular machines perform this intricate dance to keep you alive. Take a moment to appreciate the sheer complexity that makes up your existence. What part of the process blows your mind the most? Let us know! 👇 — Follow @Anatolyze if you like anatomy content! 🎥 wehi.tv ✨ Hashtags #ScienceIsCool #DNA #MolecularBiology #Biochemistry #Anatolyze #ScienceEducation #SciArt #Microscopic #Replication #CellBiology #Part4 #PartIV

Replication happened spontaneously. One shape became two. By pure chance, a compound more stable emerged. The birth of the first replicator. #Replication #SpontaneousGeneration #OriginOfLife #EarlyEarth #ScienceReels #ReelsScience

DNA replication is one of the most essential tasks of the human body. This animation by Nanographics (@nanographics.at) shows the molecular machinery which fills in the Okazaki fragments during the replication of the lagging strand. Explore more work by Nanographics on the Medical Illustration & Animation Sourcebook online site. Link in bio. #DNA #replication #research #genetics #medical #animation #medicalanimation #medicalanimators #3D #models #medicaleducation #scientificanimation #biology #molecularbiology #cellbiology

During elongation, an enzyme called DNA polymerase adds DNA nucleotides to the 3' end of the template. Because DNA polymerase can only add new nucleotides at the end of a backbone, a primer sequence, which provides this starting point, is added with complementary RNA nucleotides. This primer is removed later, and the nucleotides are replaced with DNA nucleotides. One strand, which is complementary to the parental DNA strand, is synthesized continuously toward the replication fork so the polymerase can add nucleotides in this direction. This continuously synthesized strand is known as the leading strand. Because DNA polymerase can only synthesize DNA in a 5' to 3' direction, the other new strand is put together in short pieces called Okazaki fragments. The Okazaki fragments each require a primer made of RNA to start the synthesis. The strand with the Okazaki fragments is known as the lagging strand. As synthesis proceeds, an enzyme removes the RNA primer, which is then replaced with DNA nucleotides, and the gaps between fragments are sealed by an enzyme called DNA ligase. #biology #explore #dna #genetics #premed #biochem #dnapolymerase #replication

Someday, our memories will be mere fragments, ligated by emptiness and desolation. original animation by wehimovies, review by sun, ma, tsai, abeywardana, shen & zheng 2023, Okazaki fragment maturation: DNA flap dynamics for cell proliferation and survival "DNA replication is a semi-discontinuous process. Leading-strand DNA synthesis, which is mediated by DNA polymerase ε (Pol ε), is continuous, whereas lagging-strand DNA synthesis is discontinuous. During lagging-strand DNA synthesis, a complex of DNA polymerase α (Pol α) and primase synthesize an RNA primer (7–14 nt) and a short stretch (10–20 nt) of DNA [1]. The Pol α/primase complex is then replaced by DNA polymerase δ (Pol δ), which extends the RNA–DNA primers into a series of discrete DNA fragments called Okazaki fragments [2]. The Okazaki fragment maturation (OFM, see Glossary) process, which produces an intact lagging-strand DNA from thousands to millions of Okazaki fragments, involves highly coordinated sequential reactions catalyzed by polymerases, nucleases, and DNA ligases [3,4]. First, the Pol δ-synthesized nascent DNA of the upstream Okazaki fragment extends into the downstream Okazaki fragment, producing a 5′ flap structure consisting of the RNA–DNA primer. The 5′ flap structure is then cleaved by members of the RAD2 structure-specific endonuclease family, typified by flap endonuclease 1 (FEN1), creating a ligatable DNA nick which is joined by DNA ligase I (Lig I) [5]. In addition, because Pol α has no proofreading function, Pol α-synthesized DNA fragments, which account for 1.5% of the genome [6], have a high frequency of errors [7]. To avoid DNA mutations, Pol α errors must be eliminated. A Pol α error may be endonucleolytically removed during 5′ flap cleavage. When Pol α errors occur downstream of the 5′ flap, they can be further removed by the 5′ exonuclease activity of FEN1 in complex with MutSα, followed by Lig I-directed DNA ligation [8]." #biology #dna #replication #genetics #apbio

👜Bag edition 2/3 #speeddraw #bag #purse #bagdrawing #procreate #digitalart #drawingprocess #replication #realism #coach #coachbag